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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e80c3c62db84a5671d8752bea5cdd055bd6461496c3f91a681e76da1babdcddc' 
  AND token = '761vh5asXHXGXVP6UIjdWL643+LoR41M3tQ68Vh6u6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}