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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9e89d69a0d66675f29571132e9d151cf9592bc5948a237164af6f87b9fe0c0e' 
  AND token = 'HQq/7c2oo8idCOXWnNYvtv4UFVneLPwjO9DntOOJbHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}