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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f514aadf84a90f1aa261946c543e9558d6227486e2ece035412b212088d8b729' 
  AND token = 'IoNw6Kktd7X+5fXTtogELBjrO4YxFI6kZyK+iDURpJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}