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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5110f824ed4761813c520e6dd3027bc0f6600da2e18c6474819f05c6f3ae2384' 
  AND token = 'q4+Wta5/V9xwDet3VNE1VvUzEm5z5WD6kjKFj5lA06g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}