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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f52f80b5fe8659398ed15f368ab1ef692f7f4fc0a272c3279bfd90361fcb58b' 
  AND token = 'wR7tb23mwXN4aKTbQl+PPizQreas+MNNfLKpxwGy9vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}