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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a258bce4d44f6adfeb2e5b6e4d169517bcf09c8ec6a92e5e5596a70fcd2a7343' 
  AND token = 'rZt9j4oUpTuglg3+F+SrDAQkXfcgZ58rIJDyO2gGGz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}