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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5844d3e656390918c5cd7f4eb60db2b63589617b7badec8ab18399c4609734f' 
  AND token = '6YytpkbHjJUtuP4aopmSF3RSsKplaq3B7sdm4LYYono=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}