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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03e03e9ecb508f898ad0388f83bfa5da783b09acd565c311f5969dee7db5643f' 
  AND token = 'GDRaBioFQvCEgohjhpI+yFf4tfB6BeZ89CD2u5xvSUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}