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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ffaee3fc9d6ac384dde8af27402fc834ead19bf290d6bc561fe4600ce89098' 
  AND token = 'uzyTRrZWz1khLrM6KlR97IbmjigPggJOnXqwU1J8gOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}