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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38273dd66472c9b7d110342e6589cb181f74c5f76c3e9915b62e399fe3ff39dd' 
  AND token = '8GUI6pXDfvjhaQkrOT3wfNbWaHHgPLE1s0A37WhTA/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}