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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4980a9da1f30709ed331b0ae5b32678d1e6ee2695e13162b81042e5c9be4b59e' 
  AND token = 'Tfn8GINR7gcwF7TkKlT+euzBMRRD63RO4JwtrSIz7C8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}