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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad7860e47fd69013cd6bf89bd49bc4380579b988de6ee2d9aac06d0ad9df402' 
  AND token = 'm5hBxIlaiZj+ckOxbuAUx9MyzeZucD4S+QRR8/exzjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}