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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c33559869ab6cc8129f33d2f952caa4313a8201d3e899174b091c587a657de' 
  AND token = 'Pz0TA9+3fu9uB4g6+wQ8eK+ihPMPy2Nar0f0jAMku2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}