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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e923ef1d038e975a64c4bfda029fa7a6741d0728ddbbea71e24ffebe2517299a' 
  AND token = 'nrxM94wV5akDXxQDWWQ0t6PEjl4uXtBSdLr2ZBDpznA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}