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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f5fe0960d39876eddde0abd35bc6c497cd6dfa0772dd5037a8197b0a6bce8fe' 
  AND token = 'X3NYSWCQ/1pehVYXfOA5zu4gJpydJcKz+ap7nDdDlNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}