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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69165449f550eeb2a4b99420cfa81f3ef3584480a0ce6f1e4f6b0e71cd5d5505' 
  AND token = 'IjdeuRv/Fmv0CvbUff0eocJbnjv32P02DxqeCI9+Go8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}