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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da5b80af57786d88a4f3ba94f415c8e8fa3d1952a02f9ec6c06af61c4a825885' 
  AND token = 'nuEO3sLSFf/h3iKLDKC2kKHfEMVmkH5Q43Zs6tQYc9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}