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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3178973a3ea3ba2c24a5c897442d2c3e18731b376040efcd63f57a474aeba02' 
  AND token = 'mXnc/bVdTqDNOhe10CejXcsHzxHQCiYLlnR57KPCTEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}