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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67dd25c2f40a0ca703f88d66cd8f207fef200ad30b3e18a69f43c821a6bdb58f' 
  AND token = 'lgQyFA+WOVGJmgW1Sixg9y0hUvPv1ifIWJWrRy/wSkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}