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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b161af6219b75900ebb574df0b64edc18bd15cf07173395e69393681bf7afde9' 
  AND token = 'qlcs85zmnK3zLvH5NH3FXR8W6KYKNLXbbypmQnsemSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}