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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6735d1a146f840e68a5a7201f80d5720e6de9b00ab43eac6b93869b6fabf9423' 
  AND token = 'TuSd6zCD+aVcaI4z3rKkLl+049h6NffPUQcDI8y7ZdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}