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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b615a186dc617339dda64e46e35205dc14612c60e53a5401b2e3a616bd0e4a2' 
  AND token = 'KFsu+fv5GeHwpnZwivuDPlKds6nJO+2rp0qI80btL6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}