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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '272569b808e2124dfa963bd2541d5655a74fc79ea1f925a2ded2560847d87378' 
  AND token = 'XNEE7/8XmTTGfIGT7q8PcPw1uVXySBRMGyDZ5LT7W4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}