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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49cf685c43a3f29b357f6de6a701593e89481c3b40fd93eeddd0f1bf61f5527' 
  AND token = 'c9Lbp42OFt8Kr+dvhnDZnVGl0iUG3i3Z5f82dAMZMNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}