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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16a8372095a752c1261f229686c722f311d9409d795879f53e7d88764318cbd2' 
  AND token = 'wikdX4Z9mND9J072G8mm+CyPMx+fAb6nWeL1mNn9mts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}