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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c74f33a6423f852e81e30d7740c62e290f3a66011e3de948532be0583b62d6' 
  AND token = 'eKigTgw2svaGwmU4F7vQOQMwJ/MkiWdedCIoWkDaRAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}