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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08a5be3b942366e4f35e3fee0a5f590c9a921652efebfd631f1d3e5045da7fbf' 
  AND token = 'H0O5Ip7P7xyO+I7OgMdRAeU1uyz6C8Jj4unuvdTDL1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}