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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '616d74adcc06b316118043cfeaace715470a65fc8c83d8cec8eed0bafeaa77e1' 
  AND token = 'DSR9TOi8eYkk4JwkUAqkNtiUNb8KhTSRbeiRlU9Yv9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}