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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b6143374167fa6e7397e2e363bb081d988b3a4016a32c26a5417feada8769e6' 
  AND token = 'vbU81HA8BSCr6Id9MocogxAZfjdn6uqsbX8LBIj5npo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}