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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5b27004d50e134d92fa47a20bc4bac4426649b13f757d09ee43b23e66fcfa13' 
  AND token = '0t0SRDrlgCzgZQ0Y2D47zZT+DkTS5aEQuRUvYC7BjeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}