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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8564b8514d46dd96f5b5667ec3434a1a41fd2f546fe8234604e17de872e600f' 
  AND token = 'hqulmz6ktd5lyCqgMUTuMo5Qq8j2z37lz8UbxCwf5zQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}