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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb5034cb4ec3ba5bc0572613f06dffbb14342454bcf562c3136603888355c35d' 
  AND token = 'XZpfpJlQNmTdVPrrzN1Iv6qy8Hqk6uNXTKZAzM9CIj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}