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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '981bb3c444fb17d1467dd25e7355cdabdb22b45f67835634923b89d44760bb8c' 
  AND token = '4BpE3txSMY9dPsRLdoF/aWNKYkMdtQ/ZfPh6tPyiP3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}