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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ab842481da54d62e0bc72655f40116ce01247b23b637fa5cbab3f4b93102287' 
  AND token = 'ib3vIHWFtcd7fucwBO/PyNZ/8nrUzde6Zl6POLQONyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}