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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '659ce1db6dc6178146c6ab7bf1ee89e6aefb78cb25f7ccccb3936d18a9d6ba1c' 
  AND token = 'GeOUXE3D+0WaQLYZQmBWEPOFC/5DmhGFvC3Z1etsdgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}