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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cca5e53df38ed24ebb2d1a6b05a16381b5e6e8023d6813204a299b0b01d4b88' 
  AND token = 'nbMiSgzEPhk2LdFe/gqXIBDwc+Ac9DJwITwk6qNasK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}