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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f266abb96cca3f4ed951efb557386ea6eab6adbde0c578c987370a4a3599b9cb' 
  AND token = '03dUGvPvPXJTh+AmvbIwVXmEhtDy3qRv6dUXf2CVhZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}