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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e75e84f5839961c6fc2bbd3e95a1640fdcce85b4c8c68e2b537d4dd934a04c89' 
  AND token = '9NjON05rRNZNyRgeQ7Fo18q0zldpUUSPrsRdS4aKrdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}