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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fea3d1a7b9a9d77be544aee8bff07baafe3afd8ba43456edc6204096c0a61dc' 
  AND token = 'G2P3JnKjF3/zpcMi0saL7vQb9IQ9z9GECsW3lIKXsnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}