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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48d6eba66739d1ba1afb55c2ecc7d85c75cb4342cb6912bc776199211c7af821' 
  AND token = 'fiVSoKF5pganqfB82mfSa/KDn2zdv83ImsyjU3AveqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}