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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '794c99f4d2713768e60fa632c05a8c8f1c48a08d70d09a9e8569f58e4b129354' 
  AND token = 'OvIX6yS58Pa6k8NhHlVzM92MwAS23twq9CFd0gKb6/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}