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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fb7d2da4e0799b204db1c906c3fa8bbbaf780faf887d54a4ee60a8fb9b70652' 
  AND token = 'Kjkl6AqOkuZAMEgq6npsVNFeRSV0lj9bxPeiHQ0a2DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}