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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b10978e2dfe229b9dd7583abeb7df04f95bfcac34c2bc3df98a4ba66a62bbfee' 
  AND token = '+dRpBhFSYk+UgGgBXBHv3UQcsWZ8n1aX+sAFUB3TUdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}