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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ad2250a26a702fb07893ad67718bdac043d434c307c4ff50098bfca69f230e6' 
  AND token = 'Y5Wsc7fmCP4XxpH8FITrjSuCb+zbXAdQQgMp6BcHmjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}