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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd1051f2c8b4bc8ab5f6d2ba6b411120f653f91bb573f658b1d512bde0218e8c' 
  AND token = 'c4vOLZCMnhn8kFVIAmq45zAwjBRyVzqDAp6NXgZ127o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}