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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e8e40b61ca61bea2073128f273dd7e365f46db9715438654edc1c45e0c79e2' 
  AND token = 'Bx5D9u9JLhhlsGC2PCgK956OTcDZCZyu04/Kk96c+Fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}