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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23b7820a61a52b528cf7980c3e1aa9da2f6c7ed32747d08d71546c869c03b89c' 
  AND token = 'NASKcsWZW0+OqgnOO1iR/sYyPWG6WHp57P+zrtZMtJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}