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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77de2bbc568b2141878e7439af7c444158da1ffd046020e6a5b8118feb9e8c00' 
  AND token = 'dOemNFO2F5aCOuf7tm93BJTAIiIflkDECn9HFA0jtLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}