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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df4afb9114f99dc0da030e1c742dd994cd91ca282a6229d992131a9f2c31e86e' 
  AND token = 'WQEmOwZ2omU5Fdz8bHROj4tNkidUsujGmRuBiOTJRg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}