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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d518530e731bcbb2bc523c6880f71c21d7b2ea356c215e94411ef09e7556ed6' 
  AND token = 'SfmVnlLKTgb5XW5wJKcEvBofJxjE5fBvAsZsP5jXxuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}